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Zhou, D., Zhang, J., Xiao, C., Mo, C., & Ding, B

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Dose-dependent effects of the once-daily GLP-1 receptor agonist lixisenatide in patients with type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled trial

While not appropriate for acute severe pain requiring immediate analgesia, peptides may reduce chronic pain by addressing underlying pathology that perpetuates pain signaling