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Cardiovascular side effects with semaglutide are generally mild, and the SELECT trial demonstrated a 20% reduction in major adverse cardiovascular events (MACE) in people with established heart disease

Kates has a lot of patients on GLP-1s, and she's prescribing microdoses to help patients with cycle regulation and underlying inflammatory conditions

Formulation: Some glutathione supplements come in various forms, including capsules, powders, and injections

Offer: modified-release metformin, and an SGLT-2 inhibitor If metformin is contraindicated or not tolerated, offer monotherapy with an SGLT-2 inhibitor

But with that power comes risk

Restrictive insurance policies, such as step therapy and prior authorization, which add hurdles for patients