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The introduction of N-terminal ketone motifs into genetically encoded materials and their post-translational derivatization provides a paradigm for the programmed synthesis of peptide-derived materials that more closely resemble complex natural products

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Research has identified specific gene variations that affect how individuals respond to these medications, influencing both appetite regulation and insulin sensitivity

doi: 10.1111/dom.14048 Summary Keywords incretin, GLP-1, GIP, hyperinsulinism, dumping syndrome, bariatric surgery, fundoplication Citation Danowitz M and De Leon DD (2022) The Role of GLP-1 Signaling in Hypoglycemia due to Hyperinsulinism

The burden and treatment of diabetes in elderly individuals in the US