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However, excess exposure to ROS can lead to pathological damage to human spermatozoa curtailing their competence for fertilization and disrupting their genetic integrity

Osteoblast differentiation is regulated by many signaling pathways, and abnormal activation or inhibition of these pathways may lead to imbalance of bone formation, and catalpol can promote bone effect by targeting key molecules regulating these signaling pathways (Stegen and Carmeliet, 2024)

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Professor Davids reports that some of the possible adverse side effects of long-term use include a higher risk of UV damage and skin cancer due to lower melanin levels