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Structurally, it is a 39-amino acid modified peptide, attached to a C20 fatty diacid moiety, which facilitates albumin binding

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A second principle is that animal models for the evaluation of human polyclonal antibodies or monoclonal antibodies (mAbs) should be judged with caution because FcRs that are engaged by IgGs are species-specific 23,24 , as is complement activation

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