Many peptides cause hormones to be secreted from endocrine glands
More specifically, we identified MTP, an enzyme involved in fatty acid metabolism, as the main interacting protein of GLP-1(2836) (Supplemental Table 2) and validated this by Western blotting (Figure 5B)
Importantly, this junction also represents the entry point into the pentose phosphate pathway (PPP), which shunts glucose away from energy production and instead generates NADPH, an essential cofactor required for glutathione synthesis and redox homeostasis
Frontiers in Neuroscience 15: 692217
The compound is characterised by high selectivity for GH release with markedly lower stimulation of cortisol, prolactin, and ACTH compared to earlier GHRP compounds a pharmacological profile that has made it a widely used reference peptide in endocrine and metabolic research
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