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115,116 Similarly, in GBM, quiescent and slow-cycling CD133 + CSCs have been identified alongside more proliferative CSCs, each contributing differently to tumor propagation and therapeutic resistance

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Notably, in some experiments, low-dose application of MO might have a better anti-inflammatory effect than higher doses (Kapse et al., 2017), which suggested the necessity of identifying the appropriate dosage of MO before clinical application

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