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14,15 Similarly, liver-specific Atg5 or Atg7 deletion in mice leads to spontaneous liver tumors, highlighting the role of autophagy in suppressing hepatocellular carcinoma

In particular, glucagon has firmly been demonstrated to enhance hepatic lipid metabolism, Hepatic GCGR agonism leads to upregulation of lipid catabolism pathways in the hepatocyte where a number of key regulatory transporters and enzymes facilitate beta oxidation of fatty acids (61)

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These three synthetic strategiesprodrug design, deuterium labeling, and PEGsulfonate conjugationillustrate modern medicinal chemistrys role in enhancing safety of legacy antipsychotics

Meta-analysis was performed using a random-effects model, with 13 eventually meeting the inclusion criteria