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Tell your doctor if you are pregnant or are planning to become pregnant

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Evidence shows that the secretion of incretin hormones may be impaired in some patients (particularly secretion of GLP-1 in obese individuals), but the major responsible factor is a loss of beta cell responsiveness to the incretin hormones [4]

doi: 10.1016/j.bcp.2010.04.032 153 SpencerKRMehnertJM

Acute administration of MK-801 in an animal model of psychosis in rats interferes with cognitively demanding forms of behavioral flexibility on a rotating arena

If you experience weight regain accompanied by worsening of obesity-related conditions (hypertension, diabetes, sleep apnea), prompt medical consultation is warranted to optimize your treatment plan