Side effects are mild and manageable: Bloating and GI discomfort are the most common complaints, and both can usually be resolved by splitting doses or increasing water intake
Keller et al
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Dr Tan was one of the first local doctors to be certified by the American Board of Anti-Aging Medicine
Biocompatibility and effects on macrophage viability The cytotoxicity assay revealed that CM-EVs are highly biocompatible with RAW 264.7 macrophages
Anyone choosing it over tretinoin on efficacy grounds is choosing tolerability, not evidence