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For the ICC research with HepG2 cells, human and rabbit HPX isolated by the Smith group was used (500 nM), except for the ICC studies on binding and uptake in Figures 3, 5, where proto-hemehuman HPX (CSL) was increased to 1 M (Figure 3) or 2 M (Figure 5) to increase the signal intensity

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160 mg/day for children 7-10 years

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10.3389/fphys.2021.745296 Front Physiol