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Mitophagy is a widespread and strictly maintained process of self-renewal and energy metabolism that plays an important role in reducing inflammatory responses, inhibiting reactive oxygen species accumulation, and maintaining cellular energy metabolism

Yoshida, L.R

Lancet 359 , 11211122 (2002)

The mechanisms of action of tirzepatide are multiple and need to be further investigated, but the results obtained so far suggest an effect both in improving insulin resistance and in enhancing beta cell function by restoring insulin secretion

They demonstrate slower dissociation rates (over 30 minutes) while avoiding covalent and permanent bonds that are often linked to higher dissociation constant (Kd) values (132, 133)

While both fall under the broader category of peptide therapies, they serve very different purposes