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GHRP-6, formally known as Growth Hormone Releasing Hexapeptide, is a synthetic six-amino-acid peptide with the sequence His-DTrp-Ala-Trp-DPhe-Lys-NH2

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Abbreviations AKI: Acute kidney injury ARN: Acute radiation nephropathy ACE: Angiotensin-converting enzyme AT I: Angiotensin I AT II: Angiotensin II BED: Biologically effective dose BMT: Bone marrow transplantation CKD: Chronic kidney disease CRN: Chronic radiation nephropathy DSB: Double-stranded breaks DAMP: Damage-associated molecular patterns EETs: Epoxyeicosatrienoic acids H&E: Hematoxylin and eosin IMRT: Intensity modulated radiotherapy MRT: Magnetic resonance tomography NO: Nitric oxide QUANTEC: Quantitative Analyses of Normal Tissue Effects in the Clinic RAAS: Reninangiotensinaldosterone system RN: Radiation nephropathy RT: Radiotherapy ROS: Reactive oxygen species OS: Oxidative stress TBI: Total body irradiation TGF-: Transforming growth factor beta TMA: Thrombotic microangiopathy VMAT: Volumetric arc therapy References Wild CP, Espina C, Bauld L, Bonanni B, Brenner H, Brown K, et al

A 2025 Indian skin trial showed statistically significant melasma improvement in 90 days