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These modifications were designed to reduce binding affinity for IGF binding proteins (IGFBPs), which normally sequester circulating IGF-1 and limit its bioavailability

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High-Concentration Collagen (1,000 ppm): Contains hydrolyzed collagen similar to human skin, with ultra-fine 300Da molecular weight particles for deep absorption, helping to enhance skin elasticity from within

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D., Bernard, L

This would be a significant deviation from how nutrient recommendations are normally formulated which is to base them on most peoples needs rather than outlier cases that require special treatment