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The clinical history of Fosgonimeton (Phase 2 and Phase 2/3 failures in 2022, 2023, and 2024 across mild-to-moderate Alzheimers disease and Parkinsons disease dementia / dementia with Lewy bodies) is not direct evidence about Dihexa

Specifically, an arginine has been substituted for a glutamic acid at the third position, and it has a 13-amino acid extension peptide added to its N-terminus

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10.2337/dc14-0024 [DOI] [PubMed] [Google Scholar] Araki E., Inagaki N., Tanizawa Y., Oura T., Takeuchi M., Imaoka T

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