does glp-1 affect kidneys Design and discovery of a highly potent ultralong-acting and glucagon co-agonist for attenuating renal fibrosis Glucagon-Like Peptide-1 Receptor Agonist Use

[18] Systemic side effects may include headache, irritability, restlessness, depression, fatigue, or edema resulting from fluid retention

The mechanism appears to involve both central nervous system effects (direct brain receptor activation) and peripheral effects (changes in metabolic hormones that communicate with the brain)

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Zoe Rothblatt 10:07 Hi, Conner, hi Robert, thank you so much for having me on

Researchers have proposed that rapid improvement in blood glucose control a therapeutic benefit of GLP-1 medicationsmay paradoxically worsen pre-existing diabetic retinopathy in the short term