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However, when co-administered with GLP-1R and GIPR agonism, the insulin-stimulating effects of those two pathways offset the glucagonergic glucose-raising action, while the lipolytic and thermogenic benefits of glucagon receptor signalling are preserved [3]

doi: 10.1016/j.afres.2024.100626 178 MicallefMLexisLLewandowskiP

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