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For once-daily GLP-1 injections like Victoza or Saxenda (liraglutide), time zone changes require more careful consideration

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[6] [1] The dose reduction should be individualised based on your current glycaemic control, with regular blood glucose monitoring to guide adjustments

The STEP 4 trial, which specifically examined semaglutide withdrawal, showed that participants who stopped the medication regained 6.9% of body weight over 48 weeks, while those who continued treatment lost an additional 7.9%

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What do you tell your patients