In addition to dual agonists, triple agonists hold enhanced therapeutic potential for obesity and type 2 diabetes (Table 1)
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Additionally, some studies have shown that volanesorsen, an antisense oligonucleotide that inhibits ApoC-III mRNA translation, can reduce ApoC-III levels by up to 70% in healthy individuals and 80% in patients with hyperglycemia 119,120
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Acknowledgments All data were generated in-house, and no manuscript mill was used
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