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10.1210/en.2014-1675 Endocrinology 29 HeppnerK

Consistent with this, use of a reducing source such as -mercaptoethanol allows reversal of xCT-KO phenotype, as it has been reported couple decades ago by Bannai's group ( in vivo can explain the discrepancy with in vitro phenotype

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On clinical examination, patients typically present with tense knee hemarthrosis and an inability to bear weight on the affected extremity

Each batch is manufactured by solid-phase peptide synthesis (SPPS), in which the chain is assembled one residue at a time on a solid support before cleavage and purification