Of note, the restoration of cell death by BSO co-treatment also indicates that MPA and Pyr were not inhibiting ferroptosis in an off-target manner by acting as radical trapping antioxidants (Conlon et al, 2021)
However, these findings represent associative correlations rather than direct mechanistic proof
The peptide degrades so quickly that maintaining consistent blood levels would require nearly continuous administration
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Liu, Y., Wang, Y., Liu, J., Kang, R