These effects are seen even outside of diabetes control.[ref] Decreased colon cancer mortality: A 5-year mortality study in colon cancer patients showed that GLP-1 RA use decreased mortality risk by 60% in obese patients.[ref] Decreased risk of substance abuse: A large 2026 study using data from the VA showed that GLP-1 RA drugs reduce the risk of developing a substance addiction (drugs, alcohol)
If theres a meaningful drop in appetite suppression during the dose adjustment period, some patients experience a small amount of weight regain (typically two to five pounds, much of which may be water)
The comparison between semaglutide, tirzepatide, and retatrutide reveals the rapidly advancing science of GLP-1 based treatments
Always seek the advice of your physician or other qualified healthcare provider regarding a medical condition, treatment options, or before starting any new weight loss program or medication
The GLP-1s arent fertility medications, said Dr
Use the complete dosing guide to evaluate which maintenance dose aligns with your goals
