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Patients with severe hypertriglyceridaemia (10 mmol/L) require urgent specialist referral before considering Saxenda, as both elevated triglycerides and GLP-1 receptor agonists are associated with increased pancreatitis risk
Biochimie 90 , 14861498 (2008)
The GLP-1R is expressed on a small subset of murine intrahepatic endothelial and T cells, and genetic elimination of Glp1r in these cells attenuated the anti-inflammatory actions of semaglutide in the livers of HFD-fed mice [120]
Endocrine 2019, 64, 271283
This range works well for long-term maintenance programs once initial improvement goals are achieved
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