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Generally, patients who commit to their medical weight loss program with GLP-1 and are willing to follow the diet diligently and exercise guidance secure the best results

Tricyclic antidepressants (TCAs) such as amitriptyline are associated with weight gain and potential insulin resistance, which may counteract the glucose-lowering effects of Ozempic

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Policies, prices, innovations, and patient preferences could dramatically change the market outlook, she said

The full text is on the Nature website at doi.org/10.1038/s41586-026-10444-4

Share: Popular medications such as Ozempic, Wegovy, Mounjaro, and Zepbound may offer an unexpected benefit beyond helping people lose weight and manage diabetes