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Adverse events were considered related to the treatment if they started or worsened following the start of the trial

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The effects of neuropsychiatric and addictive drugs on peripheral dopamine are not clear and need further study, although whole-body positron emission tomography (PET) scanning in mice showed that cocaine, ketamine, and methamphetamine altered dopamine concentrations in several peripheral organs (Yeh et al., 2014)

Wazana A, Bresnahan M, Kline J: The autism epidemic: fact or artifact