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Pull back plunger and drawback air to the 1 mark on the syringe

Higher concentrations mean smaller injection volumes (more convenient, less discomfort) but require more precision in measurement

For younger, healthier, lighter individuals, titration runs cautiously pushing past the efficacious dose tends to bring on undesirable side effects

But Don't Discount the Systemic Argument Entirely Now, this is where the nuance comes in

Mechanisms proposed include activation of focal adhesion kinasepaxillin pathways, stimulation of growth factor signaling, and support for nitric oxidemediated vascular responses

As I mentioned above, adequate levels of stomach acid are needed to facilitate the breakdown of B12 found in food