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Animals were treated with vehicle (Veh), Lira (300 g/day i.p.) or TZP (48 g/day s.c.) for 14 days in the following groups: Sham/Veh (n = 7), AngII/Veh (n = 15), Sham/Lira (n = 7), AngII/Lira (n = 15), Sham/TZP (n = 8), AngII/TZP (n = 15)

GLP-1 and GLP-2 Orchestrate Intestine Integrity, Gut Microbiota, and Immune System Crosstalk

Lastly, significant downregulation of metabolic pathways such as bile acid metabolism, glycolysis, fatty acid metabolism, and oxidative phosphorylation could contribute to tumor suppression by regulating anti-tumor immunity and tumor growth (Fig