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Patients should also understand realistic expectations for these medications

however, mortality was rare

In a large retrospective analysis of patients with T2DM who had received GLP-1 based therapy (n = 461,382), over 20 % of patients had nutritional deficiencies diagnosed within one year of starting treatment, with Vitamin D deficiency the most common (14 % of patients at one year), and 3 % of patients were diagnosed with muscle loss within one year [69]

Role of insulin receptor substance-1 modulating PI3K/Akt insulin signaling pathway in alzheimers disease

Anti-inflammatory effects of tirzepatide: a systematic review and meta-analysis

Subsequent trials, including SUSTAIN-6, Harmony Outcomes, and AMPLITUDE-O, reported similar MACE reductions but without a mortality benefit [15,16,17]