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Kong, Tao [56] introduced a glutathione-sensitive nanoplatform composed of cysteine-derived poly (disulfide amide) (PDSA) nanoparticles for intracellular delivery of synthetic p53 mRNA

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On analyzing the interaction of the co-crystallized ligand (Flavin-Adenine Dinucleotide, FAD) with the protein, we identified that FAD forms hydrogen bonding with Glu50, Ala130, Ser51, Thr57, Lys66, Thr339, Asp331, Gly31 and Ser30

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