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La perte de poids dpend dun ensemble de facteurs : apports caloriques, dpenses nergtiques, sommeil, masse musculaire, pathologies ventuelles et traitements en cours

Obesity significantly increases loading forces on the knees, hips, ankles, and spine, accelerating cartilage degradation and contributing to osteoarthritis development and progression

doi: 10.1007/s40262-018-0668-z

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The patient rejected psychotherapy and did not wish to use topical treatments again