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Dysbiosis disrupts intestinal integrity, leading to immune activation, oxidative stress, and inflammation, which contribute to insulin resistance, type 2 diabetes, and hypertension

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Pre-existing b12 deficiency or low-normal levels Anyone starting semaglutide with documented b12 deficiency or levels in the low-normal range (200 to 400 pg per milliliter) should receive supplementation

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In general, many individuals report improvements in pain and function within the first few days to weeks of starting BPC 157 therapy