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It remains an experimental peptide

however, caution is still warranted

The package is very nice and convenient

The mature sequence of CzEcp2 contains an Hce2 domain (Pfam: PF14856), likely putting it functionally in line with Ecp2 effectors from fungi like Dothistroma septosporum and Fulvia fulva (Mesarich et al., 2023)

Bilirubin causes protein oxidation, lipid peroxidation, decreased cellular glutathione content, increased lactate dehydrogenase levels, and nitric oxide release (via neuronal nitric oxide synthase activation via N-methyl-d aspartate receptor activation)

Proteins that are up-regulated in tumor vessels alter vascular function, and may constitute new targets for therapy as discussed further below