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The triple agonist mechanism appears to match or slightly exceed tirzepatide for blood sugar management , likely because the glucagon component, while it can raise blood sugar in isolation, works synergistically with GLP-1 and GIP activation to produce a net positive effect on glucose regulation

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Samples were then centrifuged at 200 g at room temperature for 5 min, the supernatant was discarded, and the cells were resuspended in PBS

But the mechanism is secondary, not direct

Injections are far more effective, especially for anyone with an absorption issue like pernicious anemia, Crohns disease, or a history of gastric surgery