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After a land acknowledgement by HMS diversity dean Joan Reede, NEJM editor-in-chief Eric Rubin said that when it comes to rectify[ing] injustices

Most people begin treatment with the same low dosage and slowly work their way up to a dosage that works well for them

These updates include more explicit warnings about gastrointestinal side effects, gallbladder issues, potential vision loss, and other adverse events, aiming to enhance transparency and patient awareness

Fullness is felt almost immediately on GLP-1 agonists and most patients report decreased cravings

Requirements usually include: (1) BMI 30 , or BMI 27 with at least one weight-related health condition (type 2 diabetes, high blood pressure, or high cholesterol per FDA labeling), (2) participation in a 6-month weight management program (diet, exercise, and lifestyle changes), (3) chart notes documenting BMI and health conditions, and (4) no contraindications such as personal/family history of medullary thyroid cancer or MEN2 syndrome (a rare genetic condition)

While weight reduction is a beneficial effect in type 2 diabetes management, it's important to note that Mounjaro is specifically licensed for diabetes treatment in the UK, not as a weight management medication