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Integrative modeling, molecular mechanics, and molecular dynamics evaluation of genomics variants in KMT2C (MLL3), a gene involved in Kleefstra Syndrome Type 2

Susceptibility to Oxidative Damage:Neuronal mitochondria are rich in polyunsaturated fatty acids (PUFAs), which are prone to lipid peroxidation by ROS, leading to membrane dysfunction and cellular damage

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Kojima K, Konopleva M, Samudio IJ, McQueen T, Tsao T, Zeng Z, Plunkett WK, Andreeff M

ACE inhibitors/ARBs: Improve endothelial function and reduce ROS burden

So, you know, I read it line for line