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272 MKC-3946 enhances the cytotoxicity of bortezomib and 17-AAG, while Kira8 suppresses tumor growth and potentiates bortezomib and lenalidomide efficacy in vivo

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The range of Rac1GTP-mediated immune responses to infection was determined by plotting the Rac1GTP levels in cell populations of activated PBMCs and PMNs from representative serial patient samples and found to be 3-fold above controls in samples ( Figures 3A, B )

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