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The core causative factor that plagues the human body often arise from what is known as the oxidative stress state. In this state, theres an imbalance between oxidants destroying part and antioxidants defense mechanisms in favor of oxidants, which leads to compromised health in the form of viral infections, neurodegenerative disorders, cardiovascular diseases, diabetes, autoimmune disorders, and even cancer

The current review will focus on four main areas: (1) general description of oxidative stress markers in SLE, (2) alteration of redox state and complication of disease (3) role of redox mechanisms in the initiation and execution phases of apoptosis, and (4) intracellular glutathione and its checkpoints with lymphocyte apoptosis represent novel targets for pharmacological intervention in SLE

Emerging Novel Approaches for the Enhanced Delivery of Natural Products for the Management of Neurodegenerative Diseases

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Chirieac LR, Swisher SG , Ajani JA, Komaki RR, Correa AM, Morris JS, Roth JA, Rashid A, Hamilton SR, Wu TT

Nicotinamide adenine dinucleotide has two forms one active and one inactive