Patients often report feeling mentally sharper and more emotionally balanced
Evidence snapshot: The strongest human evidence comes from a 2-year randomized controlled trial in 65 healthy older adults (Nass et al., 2008, Annals of Internal Medicine) showing sustained GH/IGF-1 increases and preserved fat-free mass, plus an earlier short-term human polysomnography study on sleep (Copinschi et al., 1997, Neuroendocrinology, PMID 9349662)
Chronic Inflammation Systemic inflammation increases oxidative burden and glutathione utilization
Andreeff M , Konopleva M, Carter B, Zhang W, Samudio I, Ruvolo P, Reed JC, Garzon R, Croce C, Champlin R, Andersson B, de Lima M, Murphy W, Plunkett W, Cortes J, Borthkaur G, Estey E, O'Brien S, Kornblau S, Berry D, Kantarjian H
13 20312036 [DOI] [PubMed] [Google Scholar] Ghibelli L., Coppola S., Rotilio G., Lafavia E., Maresca V., Ciriolo M
Many of these providers operate outside conventional medical systems and may not use standardized billing or treatment protocols