Pharmaceutical GLP-1 agonistssuch as semaglutidehave become popular, but they are synthetic, require prescriptions, and may carry side effects with long-term use
Regul Pept (1996) 63:1722
For example, the STEP 1 trial of once-weekly semaglutide (2.4 mg) in people without diabetes achieved a ~15% average body weight reduction over 68 weeks (source), with a mean baseline BMI of ~38 (source)
7 High-Sugar Foods and Sugary Drinks: These can cause general GI upset, contribute to unwanted calories, and potentially lead to blood sugar fluctuations
Holding the bottle in your hand for 1-2 minutes before dosing takes the edge off the cold without compromising stability
Valuation & Funding Noom is valued at $3.66 billion as of their 2021 Series F