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"Effects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised trial." Obesity Research & Clinical Practice

Geistlinger TR, McReynolds AC, Guy RK

Glucagon receptor activation has been associated with modest increases in calcium absorption and bone formation markers in preliminary studies, though this data is not yet definitive enough to call it a proven benefit

doi: 10.3389/fbioe.2025.1729166 Received 21 October 2025 Revised 01 December 2025 Accepted 17 December 2025 Published 15 January 2026 Volume 13 - 2025 Edited by Ling Wang, Dalian Medical University, China Reviewed by Nicola Alessio, University of Campania Luigi Vanvitelli, Italy Yesuf Adem Siraj, Bahir Dar University, Ethiopia Updates Copyright 2026 Hu, Li, Hu, Shan, Tang, Jiang, Yi, Chen, Jin, Wang and Wang