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Cancer 117 , 662666 (2005)
Consistent with the phosphorylation of Met and the subsequent signalling proteins, the dimeric macrocycles are able to clearly mimic the functional role of hHGF and induce cellular responses in not only model cell lines but also various normal human cells (Figs 4, 5, 6 and Supplementary Figs 13 and 14)
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In one aspect, the formulations or compositions described herein, and modes of administration thereof, are applicable to methods of direct perfusion of the inner ear compartments
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