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How long KLOW stays in the system functionally extends beyond serum detectability through tissue-level receptor binding and downstream pathway activation

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ROS and chromatin ROS influence the activity of epigenetic modulators, such as histone deacetylases (HDACs) or DNA methyltransferases (DNMTs) with consequences that are evident in the expression of the target genes 38,39

Quellen Raun K, Hansen BS, Johansen NL, et al

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