In addition to targeted and untargeted metabolomics in RA, integrating proteomics, transcriptomics, and genomics can help reveal the specific disease pathogenesis (68)
It is mediated by iron overload, which results in reactive oxygen species (ROS) accumulation, glutathione depletion, lipid peroxidation, and ultimately cell death [7]
Transgenic mice for in vivo epigenome editing with CRISPR-based systems
However, it is not approved for human, medical, veterinary, or household use
6 Discussion While the literature is full of evidence regarding the role of micronutrients in cancer prevention and the importance of managing deficiencies in oncologic patients, a major challenge is posed by the quality and heterogeneity of the available data
It also highlights the need for human clinical trials to fully validate the therapeutic potential of Moringa oleifera and confirm its safety for widespread use