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According to the Mayo Clinic, alcohol intolerance is caused by a genetic condition in which the body is unable to break down alcohol

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While most patients tolerate B12 shots well, mild side effects can occasionally occur, including minor pain or redness at the injection site, mild diarrhoea, or, in rare instances, an allergic reaction

Both reported pain relief and no adverse effects, but these studies are far too limited to draw conclusions about efficacy or safety in humans7