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This metabolic adaptation is a normal physiological response to weight loss and is not unique to Ozempic
Some individuals report feeling hungrier than before starting treatment, though this typically represents a return to baseline appetite regulation
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Increased fat burning : Besides improving insulin sensitivity, tirzepatide may increase fat breakdown, contributing to weight loss, especially abdominal fat
Age is relevant, with younger subjects often tolerating long-term protocols better than older subjects
For research in this area, it is the conceptual map of the melanocortin system
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