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Precauciones: pese a esta aparente inocuidad aguda, la falta de investigaciones amplias deja interrogantes

Clinical evidence comes in tiers: mechanistic studies (does the molecule do what it should at the cellular level?), animal studies (does it produce the expected effect in a living organism?), and human trials (does it actually work on the people who will use it?)

Human use is not FDA-approved, but accumulated clinical experience is reassuring: Common and mild Injection site reaction: mild redness, swelling, tenderness - resolves within hours

SY: Data curation, Formal analysis, Investigation, Methodology, Writing review & editing

Nacalai Tesque, Kyoto, Japan) dissolved in PBS every day from 5 to 8 or 12 W (EAAC1 KO mice), or from 3 to 5 W (GLAST KO mice)

Brown LS, Foster CG, Courtney JM, King NE, Howells DW, Sutherland BA