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Description

Hong YM

Cramps that are severe, frequent (occurring multiple times per day), or accompanied by muscle weakness rather than just pain may indicate a more significant electrolyte abnormality

& Said, M

It has no ring structures similar to stimulants, no alkaloid backbone resembling opioids, no diazepine structure resembling benzodiazepines, and no cannabinoid chemistry resembling THC metabolites

doi: 10.1016/j.celrep.2016.10.053 127 PeferoenLALamersFLodderLNGerritsenWHHuitingaIMeliefJet al