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Ozempic is initiated at 0.25 mg once weekly for 4 weeks, then increased to 0.5 mg weekly, with further dose increases to 1 mg or 2 mg if needed for glycaemic control

Light/dark box test The light/dark box test reliably predicts anxiolytic and anxiogenic-like effects in rodents and offers quick, easy performance without prior animal training or food/water deprivation

However, because retatrutide remains investigational, its benefits must be interpreted alongside its evolving safety profile, dose-related side effects, and the need for ongoing clinical monitoring

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These are administered by occupational health clinics, third-party testing services, or employer-contracted collection sites