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Glucose-lowering drugs or strategies, atherosclerotic cardiovascular events, and heart failure in people with or at risk of type 2 diabetes: an updated systematic review and meta-analysis of randomised cardiovascular outcome trials

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But total lean body mass also decreased by 9.7 percent

While Tirzepatide is generally well tolerated, it may cause side effects such as nausea, diarrhea, and decreased appetite, which are typically mild to moderate

Meanwhile, it hopes to have an approved pill later this year, which could enhance its growth prospects even further

The paradigm shift from glycemic control to cardiorenal risk control in diabetes places SGLT2is high on the list of pharmacologic agents to be used early in treatment