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For older adults, this includes a balanced, nutrient-dense diet with adequate protein to preserve muscle mass, alongside regular physical activity tailored to functional capacity

This work was supported by the Medical Science Research Project of Hebei (grant no

Direct evidence addressing how THC modulates BBB structure and function during aging remains scarce

Aged mice were divided into control and treatment groups, with the latter receiving intraperitoneal injections of FOXO4-DRI at doses of 0.5 mg/mL and 5 mg/kg every other day for 30 days, while controls received PBS

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Studies have shown that tetramethylpyrazine can downregulate the expression of ferroptosis-related genes (TFR1 and Atf3), upregulate the expression of protective factors (GPX4, Nrf2, and FSP1), and mitigate SLI by inhibiting iron-phospholipid generation (Wang J